Bioremodeling/biostimulating injections
What are bioremodeling agents?
Bioremodeling injections are an advanced non-surgical treatment designed to stimulate natural collagen and elastin production, improving skin firmness, hydration, and overall quality. At Hunter Coast Dermatology & Laser, we use these injectables as part of a proactive approach to skin ageing—supporting both rejuvenation and prejuvenation, the prevention of visible signs of ageing before they appear.
These treatments are ideal for patients seeking to ‘bank collagen’ early, helping to maintain skin structure and elasticity over time. By enhancing the skin’s natural regenerative processes, bioremodeling injections provide subtle, long-term improvements in skin texture, tone, and resilience, with minimal downtime.
Bioremodeling injections are commonly used in areas where early signs of ageing or skin laxity appear—such as the face, neck, décolletage, and hands. They are particularly well suited for patients noticing loss of firmness, crepey texture, or dullness, and can also be combined with other treatments such as laser therapy or anti-wrinkle injections for a layered, more comprehensive rejuvenation approach. At HCDL, these treatments are carefully integrated into a personalised skin health plan aimed at maintaining youthful structure and skin integrity over time.
All treatments at Hunter Coast Dermatology & Laser are led by specialist dermatologists or highly trained dermatology nurses under medical supervision. This ensures every treatment is grounded in clinical expertise and tailored precisely to your skin’s condition and goals. We don’t follow trends—we follow evidence, safety, and results that last.
Treatment Options

Profhilo® hyaluronic Acid
Profhilo® is an advanced injectable treatment made from pure hyaluronic acid that stimulates collagen and elastin production while deeply hydrating the skin. Unlike traditional dermal fillers, Profhilo spreads evenly beneath the skin to improve tone, elasticity, and firmness without adding volume. It is ideal for overall skin quality improvement in the face, neck, and hands, offering a refreshed, natural glow with minimal downtime.

Rejuran® Polynucleotides Eyes/Face
Rejuran® is a polynucleotide (PN)-based injectable derived from salmon DNA, known for its regenerative and anti-inflammatory properties. When used around the eyes, it helps to reduce fine lines, crepey texture, and dark circles by improving skin thickness and elasticity. For the face, Rejuran supports collagen production, enhances hydration, and restores overall skin health—making it an excellent choice for patients seeking subtle, natural-looking rejuvenation.

Rejuran® for scars
Rejuran® is also effective in the treatment of acne scars and surgical scars, where it promotes dermal healing and collagen regeneration. It works by improving skin texture, reducing scar depth, and softening the appearance of atrophic (depressed) scars. This treatment is often used in combination with laser resurfacing or q-switched laser to optimise scar remodeling and skin renewal.
Principles of rejuvenation with bioremodeling agents at HCDL
Restore Skin Quality from Within
Bioremodeling agents work beneath the surface to stimulate your skin’s natural production of collagen and elastin, improving texture, firmness, and hydration over time. At HCDL, we use these treatments not to alter facial features, but to strengthen and restore the foundational structure of your skin, resulting in subtle, natural rejuvenation.
Support Prevention and Prejuvenation
Rejuvenation doesn’t always mean reversing signs of ageing—it can also mean preventing them. Bioremodeling injectables are ideal for “prejuvenation,” helping to preserve collagen, maintain skin density, and delay the visible signs of ageing. Starting early supports long-term skin health and slows structural decline in a safe, minimally invasive way.
Integrate with a Broader Treatment Plan
At HCDL, bioremodeling injections are rarely used in isolation. We combine them with advanced laser therapies, anti-wrinkle injections, and medical-grade skincare when appropriate, delivering layered, personalised results. This integrative approach ensures improvements in skin tone, texture, hydration, and strength from multiple angles.
Frequently Asked Questions
What are bioremodeling injections, and how are they different from dermal fillers?
Bioremodeling treatments like Profhilo® and Rejuran® stimulate your skin’s natural production of collagen and elastin, improving skin texture, firmness, and hydration over time. Unlike traditional dermal fillers, they don’t add volume but instead enhance the quality and structure of the skin itself for a more natural, refreshed look.
What areas can be treated with bioremodeling agents?
These treatments are commonly used on the face, neck, décolletage, and hands. Rejuran® is also ideal for delicate areas like under the eyes and for improving the appearance of acne or surgical scars. Your clinician will recommend the most suitable product based on your skin goals and treatment area.
How many sessions will I need, and when will I see results?
Most patients require an initial series of 2–3 treatments spaced 2–4 weeks apart, depending on the product used and your skin’s condition. Results typically appear gradually over several weeks as collagen regenerates, with full benefits visible after a few months. Maintenance sessions may be recommended every 6–12 months.
Is there any downtime after treatment?
Bioremodeling treatments involve minimal downtime. You may experience mild swelling, redness, or small injection bumps immediately after the procedure, which usually resolve within 24–48 hours. These treatments are well tolerated and fit easily into a busy lifestyle.
Why choose Hunter Coast Dermatology & Laser for this treatment?
At HCDL, your treatment is guided by specialist dermatologists or experienced dermatology nurses under expert supervision. We offer a medical, results-driven approach to skin rejuvenation—focusing on long-term skin health, safety, and evidence-based outcomes that are tailored to your individual needs.
